Prelimina(?)y Report on Preparation of FIX-Deficient Plasma by Immunoaffinity Chromatography of Monoelonal Antibody
- VernacularTitle:单克隆抗体免疫亲和层析法制备缺凝血因子Ⅸ人基质血浆的初步报告
- Author:
Hailing WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Blood Transfusion
1988;0(01):-
- CountryChina
- Language:Chinese
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Abstract:
A monoclonal antibody specific for the magnesium-stabilized conformation of Factor Ⅸ(FIX)was coupled to Affi -Gel 15 to constitute an affinity chro- matographic column.When the fresh plasma passes through this column in the presence of Mg,its FIX was adsorbed exclusively,and the outflow is the finished product,a FIX-defi- cient plasma(FIX DP),with the residual FIX being very few(