Expression of protein vEGF and TGF-?1 in the process of cicatrization of incised wounds on rat skin
- VernacularTitle:大鼠皮肤切创愈合过程中VEGF,TGF-?1蛋白的表达
- Author:
Peng XIA
- Publication Type:Journal Article
- Keywords:
Skin Incised wound;
VEGF;
TGF-?1;
Injuryage;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
2007;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate whether the expression of protein VEGF and TGF-?1 can be used as an indextoestimate injuryage in the field of forensic medicine by approaching the temporal relation of VEGF and TGF-?1 expression with injury in the healing process of the incised wounds on rat skin.Methods:Experimental rat models were established by incisions made on the rat skin.the rat models were divided randomly into three groups:the experimental group,the normal group,and the postmortem injured group.The expression of VEGF and TGF-?1 were observed with Immunohistochemical techniques in their process of cicatrization.Results:In the experimental group,the expression of VEGF and TGF-?1 were higher than those in the normal control and postmortem injury group(P