HPLC Fingerprint and chemical pattern recognition method of polar components in Qingyan Dropping Pill
- VernacularTitle:清咽滴丸极性成分的高效液相指纹图谱及其模式识别的研究
- Author:
Tiejun ZHANG
;
Shiliu HAN
;
Chengwang TIAN
;
Hongji ZHU
- Publication Type:Journal Article
- Keywords:
Qingyan Dropping Pill;
fingerprint;
principal component analysis(PCA)
- From:
Chinese Traditional and Herbal Drugs
1994;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for the quality control of Qingyan Dropping Pill.MethodsAn HPLC method was developed to establish the fingerprint of polar components in Qingyan Dropping Pill,and 12 samples from various batches were analyzed.Furthermore,principal component analysis(PCA) was used to differentiate and evaluate the whole fingerprints.The relationship between Qingyan Dropping Pill and their original herbs were investigated with HPLC-DAD method.Results The result showed that liquiritin was the key component of quality control.Among the chromatographic peaks,there were six chromatographic peaks coming from Glycyrrhizae Radix et Rhizoma;Five chromatographic peaks coming from Chebulae Fructus.Conclusion This method can be used as quality control for Qingyan Dropping Pill.
