Expressions of SEDL gene and its encoded protein sedlin in a variety of tissues in mice
- VernacularTitle:SEDL基因及其编码蛋白sedlin在小鼠多种组织中表达研究
- Author:
Na HU
- Publication Type:Journal Article
- Keywords:
SEDL gene;
Sedlin;
Spondyloepiphyseal dysplasiatarda
- From:
Journal of Chongqing Medical University
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expressions of SEDL(X-linked spondyloepiphyseal dysplasiatarda,SEDL)gene and its encoded protein sedlin in a variety of tissues in mice.Methods:Real-Time PCR and Western Blot were used to detect the expression levels of the SEDL mRNA and sedlin protein in 9 tissues in mice,respectively.And the expression levels of them in bone tissues in mice of 1,2 and 4-week-old were also measured in the same way.Results:①Expressions of SEDL gene and its corresponding sedlin protein were existed in 9 tissues detected in mice.The relative expression levels of SEDL mRNA and sedlin protein in tissues in mice were significantly different (P