p75NTR expression in cultured hippocampal neurons during glutamate-induced excitotoxicity
- VernacularTitle:p75NTR在谷氨酸诱导海马神经元兴奋毒性损伤中的表达
- Author:
Lanxiang WU
- Publication Type:Journal Article
- Keywords:
Glutamate;
Excitotoxicity;
p75NTR
- From:
Journal of Chongqing Medical University
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the change in expression level ofp75NTR(p75 neurotrophin receptor)in cultured hippocampal neurons during glutamate-induced excitotoxicity.Methods:Excitotoxicity was induced by glutamate in rat cultured hippocampal neurons; RT-PCR and western blot were used to detect the change in expression level of p75NTR.Results:After glutamate exposure,p75NTR mRNA(P