Application of propofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation
- VernacularTitle:异丙酚靶控镇静在机械通气患者纤支镜肺泡灌洗中的临床研究
- Author:
Wenli CHANG
- Publication Type:Journal Article
- Keywords:
Propofol;
Target controlled infusion;
Mechanical ventilation;
Bronchoalveolar lavage
- From:
Journal of Chongqing Medical University
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of disoprofol target controlled infusion for bronchoalveolar lavage in critical patients be treated by mechanical ventilation.Methods:61 cases in ICU,who were treated by mechanical ventilation,were randomly divided into 2 groups:disoprofol group(A-group)and diazepam combined with midazolam group(B-group),monitoring and recording electrocardiogram wave form,breathing,SPO2 and blood pressure from preoperative 10 minutes to postoperative before Ramsay≤Ⅱ.Recording the time of bronchoalveolar lavage and postoperative before Ramsay≤Ⅱ,also the Patients'performance and subjective memory in the process of BAL after operation in 30 min.Results:HR and Br of A-group were much lower than B-group after operation 10 min.The restlessness,nausea, vomiting,choke cough adverse reaction rate of A-group were less than B-group during the operation.The time of BAL in A-group was shorter than B-group.A-group of awakening is faster than B-group.Surgery and painful memories in A-group were less than B-group. When propofol target control induction dose,HR,Br and SBP of A-group were much lower than B-group.Conclusion:Propofol target controlled infusion can effectively improve the stress state of patients who treated by mechanical ventilation,reducing the related side effects of BAL,such as restless,nausea and vomiting,awakening fast after operation,no pain memories,which is a good way of calm when the patients need interventional operation in Intensive Care Unit.
