Study of brain damage by cardiopulmonary bypass in infants
- VernacularTitle:体外循环术致婴幼儿脑损害的研究
- Author:
Chun WU
- Publication Type:Journal Article
- Keywords:
Cardopulmonary bypass;
Impedance coefficient;
S100;
NSE;
Brain damage
- From:
Journal of Chongqing Medical University
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore relation of Cerebral electric impedance coefficient,S100,neuron specific enolase(NSE)in serum and brain damage by the cardopulmonary bypass(CPB)in infants.Methods:40 children in 1～2-year-old who were diagnosed to be non-cyanotic congenital heart disease were selected chosen as experimental A and B group.The BOEN-BE No-injury Brain-edema-monitor was used to test Cerebral electric impedance coefficient.The selum concentrations of S100 and NSE in the different time of cardiopul-monary bypass(CPB)were measured with enzyme linked immunosorbent assa.Results:Cerebral electric impedance coefficient,S100 and NSE were significantly increased from the beginning to the end in CPB and significantly decreased gradually after operation in the dif-ferent time in A and B group(P
