Effects of extract of Alpinia officinarum Hance on learning memory consolidation and free radical in mice
- VernacularTitle:高良姜提取物对小鼠学习记忆能力的影响
- Author:
Xinxia LIU
;
Yanyan ZHAO
;
Chunsheng CHEN
;
Jie BAI
- Publication Type:Journal Article
- Keywords:
Alpinia officinarum Hance;
galangal extract;
sodium nitrite;
learning ability;
memory consolidation;
free radical;
superoxide dismutase;
maleic dialdehyde;
mouse
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To explore the effects of galangal (Alpinia officinarum Hance) extract on learning ability and memory consolidation and clearance of the free radical in mice. METHODS:Ninety mice receiving sodium nitrite to form the dysmnesic model ones,which were used to observe the walking behaviours in Morris water maze under the administration of galangal extact. SOD activity and the MDA content were measured with colorimetry,The morphological change in hippocampus slices were assessed using H-E staining and microscopic examination. RESULTS:To compare with the model group,the escape latency was markedly shortened(P
