Effect of Macleaya cordata alkaloids on five skin fungus
- VernacularTitle:博落回中生物碱对5种皮癣真菌抑制作用的初步研究
- Author:
Jing TIAN
;
Jianping YU
;
Yonghui GE
;
Liuya QI
;
Chunmei LI
- Publication Type:Journal Article
- Keywords:
Macleaya alkaloids;
skin fungus;
anti-fungus activaties
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To research inhibitory effects of plumepoppy (Macleaya cordata) extract on dermophytosis. METHODS:A series of experimental methods,including agar hole method,plate dilution method and solid medium dilution method were initiated into pathogenic organism of skin disease,including Trichophyton rubrum(Tru),Trichophyton schoenleini(Ts),Trichophyton rosaceum(Tro),Trichophyton mentagrophytes(Tm),and Epidermophyton floccosum(Ep) to determinate in vitro antibacterial Minimum inhibitory concentration(MIC) by plumepoppy extract that macerated with acidic water (pH = 3). RESULTS:Macleaya cordata alkaloids had significant effect on these five kinds of skin fungi. The MIC of Tru,Ts,Ep was 1. 6 mg/mL; The MIC of Tro and Tm was 0. 8 mg/ mL. CONCLUSION:The plumepoppy extract has anti-fungus activaties,with the increasing concentration,the inhibition effect rapidly goes up.
