Extraction and purification of water-soluble active ingredient of Ferula sinkiangensis
- VernacularTitle:新疆阿魏水溶性抗溃疡有效成分的提取纯化工艺的研究
- Author:
Xiaoqin XU
;
Liang TENG
;
Xiuyong DAI
;
Fusheng YU
- Publication Type:Journal Article
- Keywords:
Ferula sinkiangensis;
extraction process;
purification process;
uniform design
- From:
Chinese Traditional Patent Medicine
1992;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To optimize the extraction and purification of water-soluble active ingredient of Ferula sinkiangensis.METHODS: First,the comprehensive scoring system was set up to reflect the change of the extraction rate and ferulic acid coutent.in combination with the uniform design.RESULTS: The optimized extracting process was as follows: adding 8 times water and extracting twice,every time lasting 2.5 h.The optimized centrifugation purificating process consisted of: concentration ratio (1 ∶ 3),35 minutes centrifugal time,4 000 r/min rotation speed.The optimized ZTC1 + l-Ⅱ clarificant purification process was as follows: concentration ratio was 1 ∶ 22,the content of pacificator was 22% ,purification time was 1 h.CONCLUSION: The optimized extraction is available,reasonable,and reproducible.The results of pharmacodynamic test show that centrifugation is suitable to the purification of extract liquid.
