Recovery prediction of danshensu,salvianolic acid B,and salvianolic acid D in danshen ethanol precipitation
- VernacularTitle:丹参醇沉过程中丹参素、丹酚酸B和丹酚酸D的回收率预测研究
- Author:
Xiang YU
;
Biqi MO
;
Zhi WANG
;
Haibin QU
- Publication Type:Journal Article
- Keywords:
danshen(Salviae miltiorrhizae Bunge);
recovory;
ethanol precipitation;
danshensu;
salvianolic acid B;
salvianolic acid D
- From:
Chinese Traditional and Herbal Drugs
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop recovery prediction models for danshensu,salvianolic acid B,and salvianolic acid D in danshen ethanol precipitation.Methods Recorded the operation parameters of 15 normal batches of danshen ethanol precipitation in one Chinese medicine plant and measured five active component contents in danshen concentrated liquid and danshen ethanol precipitated liquid,the Stepwise-MLR recovery prediction models of dashensu,salvianolic acid B,and salvianolic acid D were developed based on an approach which combined the process parameters and the active component contents in danshen concentrated liquid.The importance of variables in the prediction models was analyzed later.Results The coefficient correlations of dashensu,salvianolic acid B,and salvianolic acid D recovery prediction models were all above 0.95.Conclusion The models developed for active component recovery prediction show a good predictability.Models can be used to help manufacturers to understand the ethanol precipitation process and improve the quality control ability of danshen ethanol precipitation.
