The minimal local anesthetic dose of bupivacaine for caesarean section in combined spinal-epidural anesthesia determined by up-and-down method
- VernacularTitle:腰硬联合麻醉用于剖宫产时布比卡因腰麻剂量的探讨
- Author:
Xiaoxia LI
- Publication Type:Journal Article
- Keywords:
Combined spinal-epidural anesthesia;
Caesarean Section;
Bupivacaine;
Minimal local anesthetic dose
- From:
Journal of Chongqing Medical University
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the minimal local anesthetic dose(MLAD) of bupivacaine for caesarean section in combined spinal-epidural anesthesia(CSEA).Methods:Designed by up-and-down,34 parturients who met the standards were given bupivacaine as planned dose gradient.Hemodynamics were monitored continuously,untoward effects were observed and APGAR of the neonates were given.Results:The MLAD of bupivacaine which is used in CSEA for caesarean section is 5.03 mg(4.1～5.1 mg),and that of ED90 and ED95 are 7.15 mg,7.89 mg respectively.Conclusion:The clinical easy to use dose of bupivacaine is 7.5 mg which is used in CSEA for most parturients.
