Effect of Edaravone Combined with Plantula Ixeridis Sonchifoliae on Relieving Neurologic Impairment Symptoms of Patients with Acute Cerebral Infarction
- VernacularTitle:依达拉奉联合苦碟子对急性脑梗死神经功能缺损症状的改善作用
- Author:
Zerong ZHENG
;
Min HUANG
;
Hui LIU
;
Jianqiang CHEN
- Publication Type:Journal Article
- Keywords:
EDARAVONE/therapeutic use;
PLANTULA IXERIDIS SONCHIFOLIAE/therapeutic use;
CEREBRAL INFARCTION/TCW-WM therapy;
NERVE FUNCTION/drug effects;
ACTIVITIES OF DAILY LIFE/drug effects
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of edaravone combined with Plantula Ixeridis Sonchifoliae(PIS) on relieving neurologic impairment symptoms of patients with acute cerebral infarction(ACI).Methods Ninety-two ACI patients were equally randomized into the treatment group and the control group.The two groups were given routine western medical treatment such as use of aspirin and neurotrophic drugs,and decreasing intracranial pressure and symptomatic treatment for large-size cerebral ischemia.Additionally,the treatment group received intravenous injection of edaravone injection plus PIS injection,and the control group received PIS injection.Fourteen days constituted one treatment course,and the treatment lasted 2 courses.The score of neurologic impairment was evaluated with European Stroke Scale(ESS),and the score of activities of daily life(ADL) was observed before treatment,and after one and two treatment course(s).The adverse reaction was recorded during the treatment.Results At the end of the first treatment course,the scores of ESS and ADL were improved in both groups(P0.05).At the end of the second treatment course,the scores of ESS and ADL were markedly improved in both groups(P