Protective Effect of Qiweibaizhu Powder against HRV Infection of Intestinal Mucosal Epithelial Cells of Suckling Mice
- VernacularTitle:七味白术散对人类轮状病毒感染乳鼠小肠黏膜上皮细胞的保护作用
- Author:
Xiao JIANG
;
Canrong WU
;
Xuefei TIAN
- Publication Type:Journal Article
- Keywords:
Qiweibaizhu Powder;
HRV;
intestinal mucosal epithelial cells;
suckling mice
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effect of Qiweibaizhu Powder against HRV infection of intestinal mucosal epithelial cells of suckling mice.Methods The 5-day-old NIH mice were made HRV diarrhea model by oral infection,and randomly divided into six groups:normal group(NG),model group(MG),Qiweibaizhu Powder group(BG),ribavirin group(ZG),suckling mice in each group were instilled corresponding drugs 3 times/d(NG and MG with normal saline) through the mouth.5 d after treatment,suckling mice were killed,small intestine stool was taken to test HRV,and pathological changes in small intestinal mucosa were observed by HE staining.Results Intestinal faeces HRV clearance of BG was significantly better than MG(P
