Study of association between ApoB/ApoA1 ratio and insulin resistance
- VernacularTitle:ApoB/ApoA1比值与胰岛素抵抗的相关性研究
- Author:
Yuanjuan JIANG
- Publication Type:Journal Article
- Keywords:
ApoB/ApoA1 ratio;
Insulin resistance
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
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Abstract:
Objective:To assess if the ratio of ApoB/ApoA1 is related to insulin resistance.Methods:673 adults living in Chongqing were enrolled.Weight,height,blood pressure,waist circumferences,fasting plasma glucose(FPG),fasting serum insulin(FINS)and lipids were measured.ApoB/ApoA1 ratio,BMI and insulin resistance index(Homa-IR)were calculated.Subjects were divided into four groups according to the quartiles of ApoB/ApoA1 ratio.Logistic regression was used to estimate the relation between ApoB/ApoA1 ratio and insulin resistance.Results:Compared with the non-insulin resistant group,the insulin resistant group is older and has on average greater mean values for BMI,systolic and diastolic blood pressure,fasting plasma glucose,triglycerides,LDL-cholesterol,and ApoB/ApoA1 ratio.In contrast,insulin resistant subjects has significantly lower HDL-cholesterol than insulin sensitive subjects(P