Analysis of prenatal screening 1648 cases in mid-pregnant women
- VernacularTitle:1648例孕中期母血清产前筛查结果分析
- Author:
Yuqin ZHANG
- Publication Type:Journal Article
- Keywords:
Down's syndrome;
Nerual tube defect;
18-trisomysyndrome;
Prenatal screening
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the value and impact of screening programme in mid-pregnancy women for the congenital fet abnormality that uses the two maternal serum markers:?-fetoprotein(AFP)and free?human chorionic gonadotrophin(free-?HCG) Methods:Serum screening of AFP and free-?HCG were offered to the 14～20 weeks pregnant Measuring the serum AFP and free ?HCGin pregnant women with ELISA,and combined with other factors:age,weeks of pregnancy,weight,etc.Measuring the high ri rate with special software.Results:Within 1 648 cases of women in the mid-pregnancy,Down's syndrom,18-trisomysyndrome an neural tube defect high risk rates in screen were 7.16%,0.61%and 2.37%respectively.1 case was confirm the Down's syndrome analysis of cytogenetics,another 2 cases was diagnosed neural tube defect via ultrasonography.Conclusion:the second trimester doub test would be effective and safe screening strategies and could be used to decrease natality of congenital fetal malformation
