Relationship between Parkinson's disease and risk factors of cerebrovascular disease
- VernacularTitle:促脑血管疾病危险因素与帕金森病相关性研究
- Author:
Jie GAO
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
IMT;
Blood glucose;
LDL-C;
Hcy;
Relationship
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relationship between some common risk factors of the cerebralvascular diseases and PD.Methods:Case-control study was carried out.Blood glucose,low density lipoprotein cholesterol(LDL-C)and homocysteic acid(Hcy) levels were detected by routine methods.The intima-media thickness(IMT)of carotid artery was measured by color Doppler ultrasound.The PD patients were graded by Unified Parkinson's Disease Rating Scale(UPDRS).Results:The blood glucose and Hcy in PD patients were higher than that in control group,and the LDL-C,IMT of carotid artery in PD were lower than that in control group.The Hcy was positively related to risk of PD,while IMT of carotid artery and LDL-C were negatively related to risk of PD by Spearman analysis.Conclusion:The Hcy level is a risk factor of PD.The LDL-C and IMT of carotid artery in PD patients were lower than that in control group,which suggests that the probability of PD patients who suffer from atherosclerosis is small.
