Expression of RHAMM gene and TPX2 gene in esophageal squamous carcinoma and its clinical significance
- VernacularTitle:食管鳞癌组织中RHAMM和TPX2基因的表达及临床意义的研究
- Author:
Ning MAO
- Publication Type:Journal Article
- Keywords:
RHAMMgene;
TPX2 gene;
Esophageal squamous carcinoma;
RT-PCR
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Toinvestigate the expression of RHAMMgene and TPX2 gene in esophageal squamous cell carcinoma(ESCC)and their relationships with clinicopathological factors.Methods:The expression of RHAMM gene and TPX2 gene were detected by reverse transcriptase polymerase chain reaction(RT-PCR)in ESCC tissues,para-cancer tissues,and matched esophageal normal mucosa tissues of 40 patients.Results:The positive expressions of RHAMM mRNA in ESCC tissues(65.0%)were significantly higher than those in para-cancer tissues(37.5%)and esophageal normal mucosa tissues(22.5%).Significant relationship was observed between positive expression of RHAMM mRNA and lymphnode metastasis(P
