FOXC1 expression in cervical cancer and endometrial cancer
- VernacularTitle:FOXC1蛋白在子宫颈癌及子宫内膜癌中的表达及意义
- Author:
Luying WANG
- Publication Type:Journal Article
- Keywords:
Transcriptional factor FOXC1;
Cervical cancer;
Endometrial cancer;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investingate potential correlations between FOXC1 expression and clinicopathologic features of endometrial cancer and cervical cancer.Methods:FOXC1 protein expression in 54 cases of cervical cancer and 23 of endometrial cancer were investigated with immunohistochemistry.Results:FOXC1 protein expression was observed in cancer tissues,including both endometrial and cervical cancer.Positive FOXC1 expression was revealed in 20(87.0%)of endometrial cancer and 29(53.7%)of cervical cancer.Significant correlation in retrospective study was observed between FOXC1 protein expression and histological grades(P0.05).Conclusion:FOXC1 may play a role in tumorigenesis of cervical cancer.FOXC1 may have no correlation with tumorigenesis of endometrial cancer.
