Measurements of Cardiac Output of a New Bileaflet Mechanical Heart Valve Prosthesis Made in China
- VernacularTitle:国产新型双叶机械人造心脏瓣心输出量的测定
- Author:
Haifang LOU
;
Aiqiang DONG
- Publication Type:Journal Article
- Keywords:
heart valve prosthesis;
cardiac output;
cardiac index;
hemodynamics
- From:Space Medicine & Medical Engineering
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the cardiac output (CO) of animals and patients underwent valve replacement with Jiuling bileaflet mechanical valve prosthesis.Methods 1) animal experiments:COs of six sheep that underwent mitral valve replacement with 21 mm prosthesis were measured with open cardiac catheterization during operation.Echocardiography and open cardiac catheterization under dobutamine stress were performed in two sheep 30 months post operation.2) patient measurements:COs of 14 cases of aortic valve and 10 cases of mitral valve replacements were measured with open cardiac catheterization,and after 12 months,they were measured with echocardiography.Results 1)animal experiments:the mean CO of 6 sheep was 2.5 L/min during operation with catheterization,and it of two sheep 30 months post-implant was 3.0 L/min with echocardiography and 2.9 L/min with catheterization.2)patient measurements:the mean cardiac index of four patients with 21 mm valve replacement was (2.55?0.27) L/(min?m2) with means of catheterization,and was (2.84?0.13) L/(min?m2) with echocardiography after 12 months.Conclusion It is demonstrated that cardiac function of animals and patients return to normal after they underwent the valve replacement with new China-made heart valve prosthesis (Juling).The new heart valve prosthesis has excellent hemodynamic performance.