Effect of Shenyuandan on Myocardial Infarct Size,Nitric Oxide Synthase and Protein Kinase C of Myocardial Ischemic Preconditioning Rat
- VernacularTitle:参元丹对大鼠心肌缺血预适应心肌梗死面积及一氧化氮合酶、蛋白激酶C的影响
- Author:
Qingxiang WEN
;
Hongzhi YANG
;
Juju SHANG
- Publication Type:Journal Article
- Keywords:
pharmacology preconditioning;
Shenyuandan;
myocardial infarcion;
NOS;
PKC;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).There were obvious expression of PKC in ischemic preconditioning group,drug pretreatment+ ischemic preconditioning group and drug pretreatment group,but the rest groups not.Conclusion Shenyuandan was able to reduce the infarct size of myocardial ischemia in rats and had a pharmacological preconditioning-like myocardial protection,its mechanism may be related to PKC-mediated mechanism.
