Suppression effects of immature dendritic cells on allogenic teeth rejection in mice
- VernacularTitle:供体骨髓来源的未成熟树突状细胞抑制小鼠同种异体牙移植后排斥反应的效果研究
- Author:
Wenying LI
- Publication Type:Journal Article
- Keywords:
Dendritic cells;
Allogenic graft;
Tooth transplantation;
Rejection
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the suppressive effects of immature dendritic cells derived from donor bone on mice allogenic teeth rejection. Methods: immature dendritic cells derived from mice bone marrow were generated with 50 U/ml granulocyte-macrophage colony-stimulating factor; the phenotype were analyzed by flow cytometry. 2?106 imDC per mouse were administered to the recipients through tail vein 7 days before allogenic teeth transplantation. The suppressive effects of imDC on transplantation rejection were observed through histological section. Results: The infiltration of lymph cell and Inflammatory reaction in allogenic teeth transplantation group were reduced after administration of imDC to the recipients.Conclusion:The allogenic teeth rejection could be lessened by imDC.
