Impact on asthma by treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis
- VernacularTitle:糠酸莫米松吸入治疗过敏性鼻炎对支气管哮喘的影响
- Author:
Chengcheng JIANG
- Publication Type:Journal Article
- Keywords:
Allergic rhinitis;
Asthma;
Inhaled-powder Salmeterol/fluticasone;
Mometasone furoate monohydrate nasal spray
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the impact on asthma by the treatment of mometasone furoate monohydrate nasal spray to allergic rhinitis.Methods:This was an opened own control study.25 patients with asthma and rhinitis were given inhaled-powder salmeterol/fluticasone50 ?g/250 ?g(Seretide),one inhalation each time,twice daily via Diskhaler for 3 months.then added the use of mometasone furoate monohydrate nasal spray(Nasonex) 50 ?g,one spray each nasal side each time,twice daily.To determine the efficacy of different treatment methods.The forced expiratory volume in one second(FEV1),the forced vital capacity(FVC),asthma symptom scores,nocturnal-awakening times and the amount of use of inhaled short-acting?2-adrenoceptor agonist bronchodilators were observed respectively before the treatment,after the treatment of salmeterol/fluticasone 50 ?g/250 ?g for 3 months,and after the treatment of inhaled-powder salmeterol/fluticasone combined with Nasonex for 3 months.Results:The treatment of inhaled-powder salmeterol/fluticasone combined with mometasone furoate monohydrate nasal spray improved FEV1,FVC and clinical asthma symptoms,and decreased the amount of the use of inhaled short-acting?2-adrenoceptor agonist bronchodilators,there were significant differences(P