The expression of SHH in gastric cancer and their clinical significance
- VernacularTitle:SHH在胃癌组织中的表达及临床意义
- Author:
Xiaoyu CHEN
- Publication Type:Journal Article
- Keywords:
Gastric cancer;
Sonic hedgehog(SHH);
Immunohistochemistry;
Therapeutics
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of sonic hedgehog(SHH) in gastric cancer,analyze the relationship with clinic pathological features,and discuss the clinical significance.Methods:Immunohistochemistry SP method was used to detect the expression of SHH in 60 cases of gastric cancer,and the relationship between protein expression and clinic pathological features was analyzed.Results:The positive expression rates of SHH was 68.3%(41/60)in gastric cancer.The expression rates of SHH was correlated with depth of invasion,lymph node metastasis,and TNM stage(P
