Small cell carcinoma of the endometrium:case report and literature review
- VernacularTitle:子宫内膜小细胞癌病例报告及文献复习
- Author:
Dong WANG
- Publication Type:Journal Article
- Keywords:
Endometrium;
Small cell endometrial carcinoma;
Pathology;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore etiology of small cell carcinoma of endometrium and clinical,histopathologic and features of the disease.Methods:We reported two case of this rare tumor and reviewed the literature.Results:Both patients presented with vaginal bleeding.Both of them underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy.Two cases were stage Ⅲc according to postoperative pathology,Pathological examination revealed small cell carcinoma of endometrium Immunohistochemical evidence of neuroendocrine differentiation was demonstrated by using markers as neuron-specific enolase,synaptophysin.Case 1 died of her disease 5months after surgery,case 2 underwent chemotherapy combined with radiotherapy and was alive with no evidence of disease for 2 months.Conclusion:Primary small cell carcinoma of the endometrium is extremely rare and aggressive disease,The outcome is very poor,Surgery combined with chemotherapy and radiotherapy may contribute to an improved prognosis.
