Influences of Dichloromethane Extraction from Crude and Processed Cornus Officinalis on Bone Marrow Cells of Aging Mice Induced by D-galactose
- VernacularTitle:山茱萸生品及制品二氯甲烷萃取部位对D-半乳糖致衰小鼠骨髓细胞的影响
- Author:
Qingchun ZHAO
;
Ju DONG
;
Liu YANG
- Publication Type:Journal Article
- Keywords:
Cornus Officinalis;
dichloromethane extraction;
D-galactose;
bone marrow cells;
mice
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influences of dichloromethane extraction from crude and processed Cornus Officinalis on bone marrow cells of aging mice induced by D-galactose. Methods DNA damage of bone marrow cells of aging mice induced by D-galactose was detected by the comet assay, the expression of p53 mRNA was detected by RT-PCR. Results The tail formation rate of model group was significantly higher than the rate of control group (P