Diterpene alkaloids from roots and processed products of Aconitum pendulum
- VernacularTitle:铁棒锤及其炮制品中二萜生物碱化学成分研究
- Author:
Yujie WANG
;
Chenjuan ZENG
;
Zhe YAO
;
Jing ZHANG
;
Yi ZHANG
;
Fan ZHANG
- Publication Type:Journal Article
- Keywords:
Aconitum pendulum Busch.;
Ranunculaceae;
diterpene alkaloid;
processing
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the diterpene alkaloids from the roots and processed products of Aconitum pendulum.Methods The chemical constituents were isolated and purified using silica gel column chromatography.Their structures were determined on the basis of NMR and mass spectra.ResultsTwelve compounds were isolated and identified as deoxyaconitine(1),3-acetylaconitine(2),aconitine(3),15?-OH-neoline(4),8-acetyl-15-hydroxyneoline(5),neoline(6),14-benzoyl-8-O-methylaconine(7),benzoylaconine(8),polyschistine D(9),benzoyldeoxyaconine(10),polyschistine A(11),and aconine(12).Conclusion Diterpene alkaloids are the main chemical constituents of A.pendulum and compounds 4—8 are found in this plant for the first time.Compared to raw materials,some boiled processed products change into new components:polyschistine D(9),benzoyldeoxyaconine(10),polyschistine A(11),and aconine(12).Identification of these components provides basis for the processing principles.
