Stimulating action of capitate phrynium stem and leaf extract on the rodent animals uterus
- VernacularTitle:棕叶茎叶提取物对啮齿目动物子宫的兴奋作用
- Author:
Zunian TANG
;
Chengfang YANG
;
Yuxian WEI
;
Ronggan LIANG
- Publication Type:Journal Article
- Keywords:
extract of Palmophyllum stem and leaf;
isolated uterus;
uterus in vivo;
exciting effect
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the exciting effects of ethanol extract of capitate phrynium(Phrynium Capitatum Willd) stem and leaf on the uterine smooth muscle of rat、mice、guinea pig and rabbit pretreated by diethylstilbestrol. METHODS: Conventional method was adopted to prepare animal uterine specimens both in vivo and in vitro.Different doses of the extract were given to the specimens and recorded their tensility,frequency and activity of contraction with the help of BL-420 biological experimental system.IC_50 of the extract was calculated,with oxytocin as standard comparison. RESULTS: 95% ethanol extract and 50% ethanol extract of capitate phrynium and leaf had obviously stimulating action on the uterine smooth muscle of rat,mice,guinea pig and rabbit in a dose-dependent manner in vitro,which include accelerating contraction frequency,raising tension(P