Determination of Allicin in Garlic Oil Sustained-release Tablets by HPLC
- VernacularTitle:高效液相色谱法测定大蒜油缓释片中大蒜素的含量
- Author:
Yonghui SUN
;
Guiji WANG
;
Ying ZHANG
- Publication Type:Journal Article
- Keywords:
Garlic oil Sustained-release Tablets;
Allicin;
HPLC;
content determination
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a determination method of Allicin in Garlic oil Sustained-release Tablets. Method Diamonsil C18 column was used with a mobile phase of mathanol-water-formic acid (80∶20∶0.1). The detective wavelength was at 218 nm. The flow rate was 1.0 mL/min. Column temperature was at 25 ℃. Results Allicin showed a good linear relationship at the range of 0.05～0.25 ?g (r=0.999 9). The average recovery rate was 99.5% (RSD=1.7%). Conclusion The method is simple, accurate, highly sensitive and reproducible. It can be used for the quantitative determination of Allicin in Garlic oil Sustained-release Tablets.
