Effects of Mycobacterium Phlei on Funcitonal States of Th_1/Th_2 in Patients with COPD and Preventive Effects on AECOPD
- VernacularTitle:草分枝杆菌注射剂预防AECOPD作用及对COPD患者Th_1/Th_2平衡的影响
- Author:
Haiping HUANG
;
Jun WU
;
Yejun YIN
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Mycobacterium Phlei;
?-Interferon(IFN-?);
Interleukin-4(IL-4)
- From:
Chinese Journal of Pharmacoepidemiology
2007;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of Mycobacterium Phlei on functional states of Th_1/Th_2 in patients with chronic obstructive pulmonary disease(COPD),and clinical effects on the prevention of acute exacerbation of chronic obstructive pulmonary diseases(AECOPD).Method:60 patients with COPD of gradeⅡwere randomly divided into a treatment group and controlled group.The controlled group were given a routine therapy,while the treatment group were given utilins in addition to the routine treatment.The contents of?-interferon(IFN-?) and interleukin-4(IL-4) in their peripheral blood and their clinical efficacy were observed before and after the treatment.Result:Before and after the treatment, IFN-?/IL-4 ratio in the treatment group was 1.39?0.20 and 1.94?0.31 respectively(P
