Analysis of 8494 patients with genitourinary tract mycoplasma infection and drug susceptibility
- VernacularTitle:8494例泌尿生殖道支原体感染及药敏分析
- Author:
Lian CHEN
- Publication Type:Journal Article
- Keywords:
Gnitourinary tract;
Gnitourinary tract infection;
Mcoplasma infection;
Drug sesceptibility
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:to investigate the status ofpatients with genitourinarytract infection caused byUreaplasma urealyticum(Uu)and Mycoplasma hominis(Mh),and its drug susceptibility and resistance in Chongqing.Methods:The genitourinary tract samples from 8 494 doubtful patients with mycoplasma infection were cultured and the susceptibility of the disease to 10 routine antibiotics was measured by mycoplasma cultivation,identification and drug susceptibility integration kit.Results:In the results of mycoplasma cultivation of 8 494 doubtful cases,2 735 cases were positive(32.2%),and 2 239 of them were simple Uu infection(26.4%),and 29 cases were simple Mh infection(0.3%)and 467 cases were double infection(5.5%).The results ofsusceptibilitytest showed that the sensitivityofUu toMinocycline,Deoxycycline,Clarithromycin,Azithromycin,JosamycinandRoxithromycinwas96.4%,95.4%,94.4%,87.1%,74.2%,and 73.3%,respectively,but tospectinomycin was 6.5%.Otherwise,the sensitivityofMh toDeoxycycline,Minocycline,Josamycin and Lincomycin was 100%,96.6%,96.6%,86.2% respectively,but toRoxithromycin,Azithromycin,Clarithromycin was 0%,0%,3.4% respectively.The double infection was the most sensitive to Minocycline and Deoxycycline,then to Josamycin,and the sensitivity was 92.1%,89.7% and 61.2%,respectively,but the sensitivityofittoRoxithromycin,Azithromycin,Clarithromycin,andSpectinomycinwas3.9%,5.2%,8.6%,and9.4%respectively.Conclusion:Mycoplasma is one of the main pathogen in genitourinary tract non-gonococcus inflammation,especially Uu infection.The therapy of mycoplasma infection should depress the production ofdrugresistant strain bythe reasonable adoption ofantibiotics accordingtothe results of susceptibilitytest.
