Optimization of Wet-shattering Extraction Process of Jingzhi Guanxin Recipe with Uniform Design Method
- VernacularTitle:均匀设计湿法粉碎提取精制冠心方的工艺研究
- Author:
Qiaoru LI
;
Wenhui SONG
;
Bo ZHAO
- Publication Type:Journal Article
- Keywords:
Jingzhi Guanxin Recipe;
Uniform design;
Wet-shattering extraction;
Process technology
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction process of Jingzhi Guanxin Recipe. Methods With the amounts of tanshinone ⅡA,salvianolic acid B,paeoniflorin,ferulic acid and hydroxysafflor yellow A as observation parameters,uniform design method was used for the optimization of wet-shattering extraction process of Jingzhi Guanxin Recipe. Results The optimum extraction process was as follows:adding 6-fold 95 %alcohol for the first time of exaction,adding 6-fold 60%alcohol for the second time,adding 6-fold 20 %alcohol for the third time,and shattering for 10 minutes every time. Conclusion This optimized process is efficient,economic and simple.
