Effect of Violet Flower Bidai Extracts on the Level of Blood Lipid and Leptin of Obese Rats
- VernacularTitle:紫花毕岱提取物对肥胖大鼠血脂及瘦素水平的影响
- Author:
Lei WANG
;
Hong CHEN
- Publication Type:Journal Article
- Keywords:
violet flower Bidai;
obesity;
leptin;
blood lipid;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of violet flower Bidai extracts on body weight,blood lipid level,serum leptin level,the activity of lipoprotein lipase and hepatic lipase of obese rats,and to discuss the mechanism of violet flower Bidai extracts on weight reduction.Methods Male obese rats which induced by high energy diet were randomly divided into four groups.All rats were given high energy diet.One control group was gavaged with normal saline and one western medicine group was gavaged with sibutramine,and two violet flower Bidai extracts groups was gavaged with water solutions of violet flower Bidai extracts at doses of 6 g(crude drug)/kg BW,12 g(crude drug)/kg BW,respectively.After six weeks,body weight,obese index,weight of abdominal fat tissue,fasting lipid,leptin in serum,the activity of lipoprotein lipase and hepatic lipase were measured.Results Body weight,obese index,weight of abdominal fat tissue in the two violet flower Bidai extracts groups were significantly lower than those in obese control group(P
