Temporary interventional pneumonectomy used as an emergency treatment for acute massive pulmonary embolism:the initial experimental results
- VernacularTitle:暂时介入性肺切除治疗急性大面积肺栓塞的实验研究
- Author:
Yong FAN
;
Yang LIU
;
Qi WU
;
Ping LI
;
Jing TIAN
;
Guijun BAO
;
Nengshu HE
- Publication Type:Journal Article
- Keywords:
pulmonary thromboembolism;
ventilation-perfusion ratio;
balloon catheter embolization
- From:
Journal of Interventional Radiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate regional airway obstruction with balloon catheter in stabilizing the vital signs in experimental animals suffered from acute massive pulmonary embolism.Methods Pulmonary embolism of right lung artery by using auto-blood clots or detachable latex balloons was established in 27 healthy sheep.When the blood oxygen saturation decreased by 25%compared to that before the procedure, the placement of balloon catheter in corresponding right main bronchus was carried out in 18 sheep(study group).Five sheep were used as control group.The blood oxygen saturation in the remaining four sheep did not reach the intervention level.The pulmonary arterial pressure,the peripheral arterial pressure,the central venous pressure,the heart rate,the blood oxygen saturation,the arterial partial pressure of oxygen as well as of carbon dioxide were invasively determined.Results The experimental model of acute massive pulmonary embolism was successfully established in 23 sheep.After the establishment of pulmonary embolism,increased heart rate,tachypnea,a decrease of≥25%in blood oxygen saturation within 30 minutes and a rise in pulmonary arterial pressure were detected.After the placement of balloon catheter in study group,a reduction of the pulmonary arterial pressure and an elevation of the blood oxygen saturation as well as the arterial partial pressure of oxygen rose were observed.The difference between study group and control group was statistically significant(P
