Effect of Jingzhui Wentong Capsule on somesthetic evoked potential,behavior and pathology of rat with cervical radiculitis
- VernacularTitle:颈椎温通胶囊对颈神经根炎大鼠体感诱发电位、行为学及病理学影响的研究
- Author:
Wanling ZHEN
;
Yanhua SHUI
;
Xuexin DONG
;
Honglian ZHANG
;
Jianping ZUO
- Publication Type:Journal Article
- Keywords:
Jingzhui Wentong Capsules (JZWT);
mimic cervical radiculitis;
SEP;
behavior;
pathology
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To observe the effect of Jingzhui Wentong (JZWT) Capsule (Ramulus Cinnamomi,Radix et Rhizoma clematidis,Radix Puerariae Lobatae,Radix Dipsaci,etc.) on somesthetic evoked potential (SEP),behavior and pathology of rat's cervical radiculitis induced by formalin. METHODS:Experiments were carried out:(1) 60 SD rats were divided randomly into 6 groups:control,model and Jingfukang groups,the high,moderate and low dose groups of JZWT Capsule. Rats of these groups were given water,Jingfukang or JZWT Capsule respectively,and SEP was tested after operation and 14 days after drugs were given to rats. At the same time,the animal behavior was observed daily. (2) 144 SD rats were divided into the same groups and given the same drugs as before. The nerve roots were taken out for pathological observation after 4,7,14,and 21 days with drug administration. RESULTS:In each drug group,the normal SEP was obviously restored,symptoms of encroached nerve were notably lightened,inflammatory reaction and proliferation tissue of mimic cervical radiculitis were more obviously alleviated than that in the model group of rat. CONCLUSION:JZWT Capsule can reduce significantly pathology change of mimic cervical radiculitis in rats,and promote the recovery of nerve function.
