Research on the Effect of Chinese Herbal Meridian Deoppilant Compound on Vascular Endothelial Cell Dysfunction of Obese Patients
- VernacularTitle:复方通络中药改善肥胖患者血管内皮细胞功能障碍研究
- Author:
Guizhi BI
;
Jun DUAN
;
Xiaolin TONG
- Publication Type:Journal Article
- Keywords:
obesity;
endothelial dysfunction;
blood lipid;
Chinese herbal meridian deoppilant compound;
Xinxiang Shuluo 2# capsules
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of Chinese herbal meridian and vessel deoppilant compound on the dysfunction of endothelium-dependent dilation (EDD) of simple obesity patients, and explore its mechanism. Methods Sixty-five obese patients with dysfunction of EDD (denoted by FMD: flow mediated brachial artery vasodilatation rate) were found through the prehminary high-resolution vascular ultrasound check, and randomized into the therapy group (treated with Chinese herbal meridian and vessel deoppilant compound) and the control group. The therapy group took Xinxiang Shuluo 2# capsules three times a day, 3 gram each time, and the control group was given the same doses of starch capsules. The experiment lasted 12 weeks. Before and after the experiment, FMD and inner diameter of brachial arteries (DO) of all the patients were measured, and the changes of total cholesterol (TC) and trigiyceride (TG) in serum were compared. Results FMD of the therapy group was significantly higher than the control group (P
