Effect of Rosuvastatin on Carotid Arterial Intima-media Thickness of Elderly Patients
- VernacularTitle:瑞舒伐他汀对老年患者颈动脉内膜中层厚度的影响
- Author:
Yanhong WANG
- Publication Type:Journal Article
- Keywords:
Rosuvastatin;
Simvastatin;
Elderly patients;
Carotid arterial intima-media thickness
- From:
Chinese Journal of Pharmacoepidemiology
2005;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of rosuvastatin on carotid arterial intima-media thickness of elderly patients and its comparison with simvastatin.Method:126 patients hospitalized during January and August 2008 were randomly divided into a treatment group and a cotrolled group.All the patients were male and older than 70 years old,and their mean age was 78.9?8.8 years.63 patients accepted the rosovastatin therapy and 63 patients accepted the simvastatin therapy.Result:After 8-weeks'therapy,CIMT was reduced from 1.58?0.24mm before the treatment to 1.44?0.22mm after it.There was no difference between the two groups in decreasing CIMT.No adverse events related to the study medication were observed.Conclusion:The treatment with rsuvastatin can prevent the increase of carotid arteriosclerosis in eldlerly patients without any difference in decreasing CIMT,compared with simvastatin.
