The regulation investigation of the interaction between TACE and TGF-?
- VernacularTitle:TACE-TGF-?相互作用参与胚泡着床的机制研究
- Author:
Huan YANG
- Publication Type:Journal Article
- Keywords:
Blastocyst implantation;
Tumor necrosis factor alpha converting enzyme(TACE);
Transforming growth factor-?(TGF-?);
Endometria;
Immunochemistry;
RT-PCR
- From:
Journal of Chongqing Medical University
2007;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feedback regulation of transforming growth factor ?(TGF-?)to tumor necrosis factor-? converting enzyme.Methods:Reverse transcription polymerase chain reaction(RT-PCR)and immunochemistry were applied to detect TACE mRNA and protein in mice endometria of experiment group(TGF-? antibody was injected)and control group(saline was injected).Results:The expressions of TACE mRNA and protein in control group were higher than in experiment group.Conclusion: TGF-? could feedback on TACE expression in mice endometria and TACE-TGF-?-EGFR might one of the regulations during blastocyst implantation.
