Study on Preparation Technique of Jiegeng Zaogan Capsules
- VernacularTitle:桔梗皂苷胶囊制备工艺的实验研究
- Author:
Qin CHEN
;
Chen CHEN
;
Ling LV
;
Ying CUI
;
Yan WANG
- Publication Type:Journal Article
- Keywords:
Jiegeng Zaogan capsules;
Platycodins D;
Preparation technique;
Orthogonal test;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the preparation technique for Jiegeng Zaogan capsules (capsules of total saponins from the roots of Platycodon grandiflorum A.DC).Methods The optimal preparation technique for Jiegeng Zaogan capsules was investigated by L9(34) orthogonal test with the Platycodin D content as the observation index.Results The optimized extraction procedure was as follows:extracting for 3 hours each time and 3 times in total,adding 10-fold water,alcohol sedimentation concentration at 65 %,and alcohol sedimentation solution staying for 48 hours.Conclusion The preparation process of Jigeng Zaogan capsules is reliable with stable quality,which offers a feasible method for the industrialization production of the capsules.
