Research on Refining of Radix Sophorae Flavescentis Decoction by Microfiltration-Ultrafiltration Technology
- VernacularTitle:微滤-超滤法精制苦参水煎液的工艺研究
- Author:
Hongning GAO
;
Wanqin JIN
;
Liwei GUO
- Publication Type:Journal Article
- Keywords:
Microfiltration;
Ultrafiltration;
Alcohol sedimentation method;
Radix sophorae flavescentis decoction
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the refining of Radix Sophorae Flavescentis (RSF) decoction by microfiltration combined with ultrafiltration method,and to compare the refining effect with that refined by alcohol sedimentation method.Methods HPLC was applied to analyze the content of oxymatrine,ultroviolet (UV) spectrophotometry was used to determine the content of total flavonoids in RSF decoction,and suitable concentration of NaOH solution for the detergent were chosen in order to wash the membrane.Results The refining effect is better and the recovery ratio of efficient components is higher in RSF decoction refined by microfiltration combined with ultrafiltration method than in those refined by alcohol sedimentation method.Microfiltration combined with ultrafiltration method is of simple operation and short period,and ultrafiltration membranes can be easily washed.Conclusion The microfiltration combined with ultrafiltration method can be used as the alternative for the traditional alcohol sedimentation method in refining of RSF decoction.
