Effects of Ginsenoside Re on MDA Content and SOD Activity in Rats with Exercise-induced Fatigue
- VernacularTitle:人参皂苷Re对运动性疲劳模型大鼠MDA含量和SOD活性的影响
- Author:
Yichong FENG
;
Ziming ZHAO
;
Yuan CHEN
;
Huashan PAN
;
Jiahong LI
;
Bogao BIAN
;
Xi WEN
- Publication Type:Journal Article
- Keywords:
Ginsenoside Re;
Exercise-induced fatigue;
Rats;
Malondialdehyde (MDA);
Superoxidedismutase (SOD)
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective This report describes the mechanism of Ginsenoside Re to resist Exercise-induced fatigue based on the observation of effects on MDA content and SOD activity.Methods Thirty male SD rats were divided into 3 groups randomly:Ginsenoside Re group,model group and control group,10 rats in each group.Rats in Ginsenoside Re group were given gastric gavage of Ginsenoside Re once a day,while rats in model and control groups were given the same volume of normal saline.One hour after administration,rats of Ginsenoside Re groups and Model groups received medium-intensity treadmill exercise for 20 minutes at the speed of 15m/min,with a slope of 0 degree,and after 40-mimute break repeated it for another 20minutes.Fourteen days later,MDA content and SOD activity have been tested.Results MDA content in the serum,liver tissue and muscle tissue of Ginsenoside Re group was obviously lower than that in the model group (P
