Effect of Shexiang Baoxin Pill on endothelial in stable angina pectoris patients and its underlying mechanisms
- VernacularTitle:麝香保心丸对冠心病血管内皮功能的影响及其作用机制
- Author:
Huanqing CHEN
;
Xiaoqiang XIONG
;
Zhaohui DUAN
;
Fengru ZHAO
;
Zhijuan HAN
;
Xiangkui ZHANG
- Publication Type:Journal Article
- Keywords:
Shexiang Baoxin Pill(SXBXP);
stable angina;
clinical study;
endothelial;
mechanisms
- From:
Chinese Traditional Patent Medicine
1992;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of Shexiang Baoxin Pill(SXBXP) on endothelial in stable angina pectoris patients and its underlying mechanisms. METHODS: Sixty-eight stable angina pectoris patients were randomly divided into two groups,the conventional group(34cases),SXBXP treatment group(34cases).The conventional group was treated with standard treatment,and SXBXP group was treated with standard treatment and SXBXP.FMD,NO,ET,TXB_2,6-Keto-PGF-1a were determined before and after three months treatment. RESULTS: FMD,NO,6-Keto-PGF-1a of SXBXP group were (9.35%?0.78%)、(77.25?6.36)?mmol/L、(93.87?(10.28))?/(ng/L) after treatment,ET、TXB_2 were(81.15?5.43) pg/mL、(43.02?4.19)?/(ng/L).There were significant improvement as compared with in SXBXP group before treatment and in conventional group after treatment(P