Specific Spectral Domain Optical Coherence Tomographic Findings of Oguchi Disease.
10.3341/jkos.2012.53.7.1041
- Author:
Joo HYUN
1
;
Tae Kwann PARK
;
Jee Ho CHANG
;
Young Hoon OHN
Author Information
1. Department of Ophthalmology, Soonchunhyang University College of Medicine, Bucheon, Korea. genophilus@hanmail.net
- Publication Type:Case Report
- Keywords:
Dark adaptation;
Electroretinography;
Mizuo-Nakamura phenomenon;
Oguchi disease;
Optical coherence tomography
- MeSH:
Adolescent;
Dark Adaptation;
Electroretinography;
Humans;
Night Blindness;
Reflex;
Retinal Pigment Epithelium;
Tomography, Optical Coherence
- From:Journal of the Korean Ophthalmological Society
2012;53(7):1041-1045
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report specific spectral domain OCT findings of Oguchi disease diagnosed with fundoscopic examination and electrophysiological study. CASE SUMMARY: A 14-year-old patient visited our clinic with a complaint of night blindness for ten years. Fundoscopic examination showed a golden-yellow fundus reflex. After three hours of dark adaptation, the fundus color returned to normal (Mizuo-Nakamura phenomenon). In full-field ERG, rod b-wave was not detectable. The a-wave amplitude in maximal combined response increased after three hours of dark adaptation, although the b-wave amplitude was similar to the amplitude before dark adaptation, demonstrating a negative waveform. In the spectral domain OCT images of the perifoveal area, no gap between the retinal pigment epithelium and the inner segment/outer segment (IS/OS) junction was detected before prolonged dark adaptation, and a highly reflective band was shown. However, the gap appeared after three hours of dark adaptation, and two highly reflective bands were detected in the OCT images. CONCLUSIONS: The characteristic OCT finding in addition to the specific fundoscopic finding and full-field ERG results may be useful to diagnose Oguchi disease.
