Effect of Acupuncture on Apoptosis and Protein Caspase-9 Expression in Hippocampus of Cerebral Ischemia Rats
- VernacularTitle:针刺对脑缺血大鼠海马区凋亡细胞及Caspase-9蛋白表达的影响
- Author:
Huifang MA
;
Caixia LIN
;
Xiujun REN
- Publication Type:Journal Article
- Keywords:
cerebral ischemia;
acupuncture;
Caspase-9;
apoptotic cell;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of acupuncture on apoptosis and Caspase-9 expression in hippocampus of cerebral ischemia (CI) rats. Methods Thirty male SD rats were randomized into control, CI and CI + acupuncture group, with 10 cases in each group. CI model was established by occlusion of the unilateral middle cerebral artery. "Baihui" (GV20) and "Shuigou" (GV26) were acupunctured once daily for 7 days. The apoptosis and expression of protein Caspase-9 in hippocampus was displayed by HE staining and immunohistochemical method. Results In comparison with the normal control group, Caspase-9 immune reaction (IR) positive cells in the hippocampus of CI group increased significantly (P
