Elastase-induced intracranial aneurysm by means of endovascular balloon occlusion:preparation of animal model and progress in its applications
- VernacularTitle:血管内球囊阻断结合弹力酶诱导法制作颅内动脉瘤动物模型及应用进展
- Author:
Qianyu XIE
;
Chuan LU
;
Xuemei JIANG
- Publication Type:Journal Article
- Keywords:
aneurysm;
animal model;
endovascular;
endovascular occlusion;
elastase
- From:
Journal of Interventional Radiology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
It is of capital importance to establish a reliable experimental animal model of intracranial aneurysm which should be extremely similar to human intracranial aneurysm in histological and hemodynamic aspects.For recent years,the elastase-induced aneurysm model by means of endovascular balloon occlusion has been widely used abroad.This paper aims to review the preparation of animal mode,the advantages and disadvantages of such a model as well as the recent progress in its applications.