The determination of liver reserve function before chemoembolization in patients with primary hepatocellular carcinoma:its clinical significance
- VernacularTitle:原发性肝癌患者介入化疗栓塞前肝储备功能测定的临床价值
- Author:
Quanjun YAO
;
Wusheng LU
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
primary hepatocellular carcinoma;
transcatheter arterial chemoembolization;
hepatic reserve function;
clinical value
- From:
Journal of Interventional Radiology
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical usefulness of determining the liver reserve function by estimating the retention rate of indocyanine green at fifteen minutes(ICGR15) before interventional chemoembolization in treating patients with primary hepatocellular carcinoma(HCC).Methods Forty-three patients with HCC were enrolled in this study.Before interventional chemoembolization ICGR15 and Child-Pugh classification were estimated in all patients.Based on the ICGR15,the patients were divided into three groups.After chemoembolization,all the patients were divided into two groups according to liver function condition: group M(showing mild hepatic dysfunction) and group S(developing severe hepatic dysfunction).The occurrence of postoperative hepatic dysfunction and the difference in the hepatic function changes between three groups were analyzed.Results After interventional chemoembolization the occurrence of hepatic dysfunction were significantly different between three groups divided by ICGR15 test(P