Effect of Zhibai Dihuang Pill on serum level of resistin,adiponectin,leptin in patients with hyperthyroidism
- VernacularTitle:知柏地黄丸对甲状腺功能亢进症患者抵抗素、脂联素及瘦素的影响
- Author:
Qing XUE
;
Hua ZHANG
;
Suling CAI
;
Yanan WANG
;
Liao SUN
- Publication Type:Journal Article
- Keywords:
hyperthyroidism;
resistin;
adiponectin;
leptin;
Zhibai Dihuang Pill
- From:
Chinese Traditional Patent Medicine
1992;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To investigate the effect and the mechanism of Zhibai Dihuang Pill(Radix Rehmanniae praeparata,Fructus Corni,Rhizoma Dioscoreae,Rhizoma Anemarrhenae,Cortex phellodendri Chinensis,etc.) on patients with hyperthyroidism. METHODS: Eighty-five hyperthyroid patients were randomly divided into two groups.The control group(40 cases) were treated with propylthiouracil,while the treatment group(45 cases) were treated with propylthiouracil and Zhibai Dihuang Pill;in the 12-week long treatment period,the heart rate,body weight,thyroid free FT_3、FT_4 and TSH and the serum level of FAA,resistin,adiponectin,leptin of patients in both groups were measured. RESULTS: After treatment,the heart rate,the serum of FT_3,FT_4 decreased and the body weight,TSH increased in both groups(P0.05).(CONCLUSION): Zhibai Dihuang Pill can improve the abnormal metabolism of sugar and fat in patients with hyperthyroidism by its actions on the serum level of FFA,resistin,adiponectin,leptin.
