The role of IFN-?,TNF-? and IL-10 in the rat model for chronic abacterial prostatitis
- VernacularTitle:IFN-?、TNF-?和IL-10在慢性非细菌性前列腺炎大鼠中的表达及意义
- Author:
Hongzhi WANG
- Publication Type:Journal Article
- Keywords:
Prostatitis;
IFN-?;
TNF-?;
IL-10;
Dysimmunity
- From:
Journal of Chongqing Medical University
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the role of IFN-?,TNF-? and IL-10 in CAP rats and approach the pathogenesis of CAP.Methods:20 Aged Sprague Dawley rats were randomly divided into two groups: the control group(10 rats) and the rat model for CAP group(10 rats).The changes of prostate gland inflammation was investigated by HE stain.The expression of IFN-? and TNF-? in rat prostatic tissue was detected by immunohistochemistry (sp). The expression of IL-10 in rat prostatic tissue was detected by enzyme linked immunosorbent assay (ELISA). Results:(1) The CAP model group's histopathology express the obvious inflammation performance;(2) The IFN-?,TNF-? and IL-10 in the rat model for CAP group were higher than the control group (P
