Efficacy of thyroid hormone treatment and the serum levels of thyroid hormone in patients with primary nephritic syndrome
- VernacularTitle:慢性肾脏病患儿小剂量甲状腺素治疗的作用及甲状腺激素水平变化的意义
- Author:
Yajun WANG
- Publication Type:Journal Article
- Keywords:
Chronic kidney disease;
Hormone;
Therapy;
Children
- From:
Journal of Chongqing Medical University
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy of low-dose thyroid hormone treatment and the change in levels of thyroid hormone in patients with chronic kidney disease. Methods: 92 children with chronic kidney disease were randomly divided into thyroxine treatment group and control group, with 46 children in each group. All patients received conventional treatment, the treatment group served with additional Levothyroxine of 25 ~ 50?g/d. At least 1 month follow-up was taken to compare the clinical efficacy, RIA detection level of thyroxine. Results: In control group ,urinary protein, urine occult blood, Hb and albumin showed no changes at 1w-4w after therapy, and the treatment group also showed this trend. There were no difference between two groups. However, 1 week after treatment, SCr and BUN began to decline, till 4th week(P