Clinical results of chemotherapy applying docetaxel-cisplatin combination for advanced hormone independent prostate cancer
- VernacularTitle:多西他塞联合顺铂治疗晚期激素非依赖性前列腺癌的临床分析
- Author:
Weiyang HE
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Adjuvant;
Chemotherapy;
Carcinoma
- From:
Journal of Chongqing Medical University
2007;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy and toxicity of docetaxel and cisplatin for treatment of hormone independent prostate cancer. Methods:Thirty-two cases hormone independant prostate cancer patients were enrolled in this study. All patients had received castration and/or anti-androgens but relapse with elevated PSA. Multiple metastasis were diagnosed by imaging approach. Before chemotherapy,there were 26 cases suffered from pain by bone metastasis. Docetaxel 75 mg/m2 + NS 250 ml was administered intravenously and cisplatin 100 mg/m2 +NS 500 ml was administered intravenously on the first days. Results:Levels of PSA decreased to normal(
